Labor is treated as any other factor of production, ex: Money, Material, Land, etc. Wages were decided on the basis of demand and supply forces. Human resources was referred as вЂњa commodityвЂќ to be bought and sold. The evolution of human resources development can be easily understood in the following chronological sequence: The Commodity Concept What is the Historical Perspective of Human Resources Development? HRD as an activity and as a process plays a crucial and noteworthy role identifying the hidden potential of the workforce employed in the organization and to polish their skills, technical knowledge in order to develop them and to prepare them for facing the challenges on their own. Human resources development aims at assisting people to acquire competencies that are being required to perform their duties in an efficient manner and to let the organization ripe the fruits of their know-how and talents. What are the aims of Human Resources Development?

Thus, human resource development is the process of developing the human resource working in an organization by modernizing their knowledge and upgrading their skills, attitudes and perceptions in order to meet out the changing trends of the globalized economy and also to utilize those developments for the attainment of the organizational goals. Development: Is the acquisition of capabilities that are needed to perform the present job or the future expected job.Human resources: Who are considered to be the lifeblood of any organization, are the people and their characteristics at work either at the national level or organizational level.The term вЂњHuman Resources DevelopmentвЂќ consists of two words i.e. The human resources department of an organization performs human resources management, overseeing various aspects of employment, such as compliance with labor law and employment standards, administration of employee benefits. This article talks about the difference between Human Resources Development and Human Resources Management. Here, we discuss the premise of HRD testing in HGSOC, current methodologies for HRD identification and their performance in the clinic, highlight upcoming strategies, and discuss the challenges faced in moving this field forward.Have you ever wondered what the вЂњHuman ResourcesвЂќ is? What does the Human Resources do? What are the differences between вЂњHuman Resources DevelopmentвЂќ and вЂњHuman Resources Management?В The Human Resources are the ones who make-up the workforce of an organization, business sector or economy. It is thus critical that HRD testing is optimized to address the controversies of diverse HRD testing methodology, appropriate thresholds for HRD identification, and relevant timepoints for HRD testing, in order to realize the potential for PARPis to maximally benefit patients with HGSOC. In practice, this means that restoration of HRR through mechanisms of platinum and PARPi resistance are not adequately represented by genomic scar assays, and contribute toward discordance with clinical PARPi response, or lack-thereof. Yet despite the rapid maturation of this field, tumoral HRD status has been recognized to be dynamic over time and with treatment pressure. At present, clinical-grade assays such as mењњhoice CDx and FoundationOne CDx are approved companion diagnostics which can identify patients with HRD-positive HGSOC by diagnosing a вЂgenomic scarвЂ™ reflecting underlying genomic instability. Recent data have drawn attention to the assessment of homologous recombination DNA repair (HRR) as a prognostic and predictive biomarker in HGSOC, leading to increasing debate on the optimal means of defining and evaluating HRD, both genotypically and phenotypically. Poly(ADP-ribose) polymerase inhibitors (PARPis), developed based on the rationale of synthetic lethality that predicates antitumor efficacy in tumors harboring underlying HRD, now represents an important class of therapy for HGSOC. The recognition of homologous recombination deficiency (HRD) as a frequent feature of high-grade serous ovarian cancer (HGSOC) has transformed treatment paradigms.

What is hrd testing